Pentosan Polysulphate Sodium
About Pentosan Polysulphate Sodium
Pentosan Polysulphate Sodium is a low-molecular-weight heparin-like compound used to provide relief from bladder pain and discomfort associated with intestinal cystitis. Intestinal cystitis is a disease that causes scarring and swelling of the bladder wall. It is a painful bladder syndrome with bladder pressure, bladder pain, and pelvic pain.
Pentosan Polysulphate Sodium contains Pentosan polysulphate sodium, which works by preventing irritation of the bladder walls by binding to the mucosal membrane of the bladder. This helps in preventing the irritating chemicals present in the urine to come in contact with the bladder wall. Thereby, Pentosan Polysulphate Sodium provides relief from the discomfort associated with intestinal cystitis.
You are advised to take Pentosan Polysulphate Sodium for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as stomach upset, headache, dizziness, diarrhoea, and heartburn. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Consult your doctor before taking Pentosan Polysulphate Sodium if you are pregnant or breastfeeding. Pentosan Polysulphate Sodium may cause dizziness, so drive only if you are alert. Pentosan Polysulphate Sodium is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol along with Pentosan Polysulphate Sodium as it could lead to increased dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects.
Uses of Pentosan Polysulphate Sodium
Medicinal Benefits
Pentosan Polysulphate Sodium belongs to a group of medicines called low-molecular-weight heparins used to provide relief from bladder pain and discomfort associated with intestinal cystitis. Pentosan Polysulphate Sodium works by preventing irritation of the bladder walls by binding to the walls of the bladder. This helps in preventing the irritating chemicals present in the urine to come in contact with the bladder wall. Thereby, Pentosan Polysulphate Sodium provides relief from the discomfort associated with intestinal cystitis.
Directions for Use
Storage
Side Effects of Pentosan Polysulphate Sodium
- Stomach upset
- Dizziness
- Headache
- Diarrhoea
- Heartburn
Drug Warnings
Do not take Pentosan Polysulphate Sodium if you are allergic to any of its contents. Inform your doctor if you have a bleeding disorder, eye problems, stroke, stomach ulcer, intestinal polyps, aneurysm (enlargement of an artery), haemophilia, ulcers, low platelet count, intestinal blockage, spleen disease, liver or kidney problems. Consult your doctor before taking Pentosan Polysulphate Sodium if you are pregnant or breastfeeding. Pentosan Polysulphate Sodium may cause dizziness, so drive only if you are alert. Pentosan Polysulphate Sodium is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol along with Pentosan Polysulphate Sodium as it could lead to increased dizziness.
Drug Interactions
Drug-Drug Interaction: Pentosan Polysulphate Sodium may have interaction with a blood thinner (warfarin, aspirin)
Drug-Food Interaction: No interactions found/established.
Drug-Disease Interaction: Inform your doctor if you have a bleeding disorder, eye problems, stroke, stomach ulcer, intestinal polyps, aneurysm, haemophilia, ulcers, low platelet count, intestinal blockage, spleen disease, liver or kidney problems.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionAvoid consumption of alcohol while taking Pentosan Polysulphate Sodium as it may cause increased dizziness.
Pregnancy
cautionPentosan Polysulphate Sodium belongs to pregnancy category B. Please consult your doctor if you are pregnant or if you have any concerns regarding this. Your doctor will prescribe Pentosan Polysulphate Sodium only if the benefits outweigh the risks.
Breast Feeding
cautionConsult your doctor if you are breastfeeding; your doctor will decide if Pentosan Polysulphate Sodium can be taken by breastfeeding mothers or not.
Driving
cautionPentosan Polysulphate Sodium may cause dizziness. Do not drive or operate machinery unless you are alert.
Liver
cautionLimited information is available regarding the use of Pentosan Polysulphate Sodium in patients with liver problems. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Kidney
cautionLimited information is available regarding the use of Pentosan Polysulphate Sodium in patients with kidney problems. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
unsafePentosan Polysulphate Sodium is not recommended for children below 16years as the safety and effectiveness have not been established.
Habit Forming
Diet & Lifestyle Advise
- Maintain a healthy diet and exercise regularly as it helps in improving overall health and boosts self-esteem.
- Avoid citrus fruits and spicy food.
- Limit intake of caffeine, carbonated beverages, and alcohol.
- Consume mild sweet potatoes, pears, and blueberries.
- Perform meditation and yoga. This helps in relieving stress and provides relaxation.
- Follow a regular sleep pattern to improve the amount and quality of sleep you get.
- Learn relaxation skills as they help in reducing stress.
- Avoid smoking.
- Wear loose and comfortable clothes.
- Try to urinate less often once the pain is under control.
- Pelvic floor exercises and manipulative physical therapy may help reduce tenderness and pain.
Patients Concern
Disease/Condition Glossary
Intestinal cystitis: It is a disease that causes scarring and swelling of the bladder wall. It is a painful bladder syndrome with bladder pressure, bladder pain, and pelvic pain. The pain could be mild or severe. Intestinal cystitis is more common in women than in men. Symptoms include pelvic pain, urgent and persistent need to urinate, frequent urination, and pain during sexual intercourse. Although the signs and symptoms of intestinal cystitis are similar to urinary tract infection, usually there is no infection. However, the symptoms may worsen if a person with intestinal cystitis gets an infection in the urinary tract.
FAQs
Pentosan Polysulphate Sodium is low-molecular-weight heparin-like compound used to provide relief from bladder pain and discomfort associated with intestinal cystitis.
Pentosan Polysulphate Sodium works by preventing irritation of the bladder walls by binding to the walls of the bladder. This helps in preventing the irritating chemicals present in the urine to come in contact with the bladder wall. Thereby, Pentosan Polysulphate Sodium provides relief from the discomfort associated with intestinal cystitis.
Pentosan Polysulphate Sodium may cause unusual bleeding or bruising. Be cautious while using sharp objects and while doing any activities which might cause injury. Consult a doctor immediately if you notice unusual bleeding or bruising, such as blood in stools or urine, nosebleed, rectal bleeding, heavy gum bleeding, or bloody vomit.
Do not discontinue Pentosan Polysulphate Sodium without consulting your doctor as it could lead to recurring or worsening of symptoms. To treat your condition effectually continue taking Pentosan Polysulphate Sodium for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Pentosan Polysulphate Sodium.
Diarrhoea could be a side-effect of Pentosan Polysulphate Sodium. Eat non-spicy meals and drink plenty of fluids if you experience diarrhoea. Consult your doctor if you have severe diarrhoea or if you find black/tarry stools or blood in stools.
Please consult your doctor before taking anti-coagulants along with Pentosan Polysulphate Sodium. This medicine might increase the risk of bleeding as it has a weak anticoagulant effect.
Pentosan Polysulphate Sodium may cause side effects such as diarrhoea, headache, dizziness, heartburn and stomach upset. If these side effects persist or worsen, please consult your doctor.
No, Pentosan Polysulphate Sodium is not a steroid. It is used in the treatment of interstitial cystitis also known as painful bladder syndrome. This disease may cause sores on the inner lining of the urinary bladder along with areas of tiny bleeds, and the patient complains of pain and a frequent urge to urinate.
It usually takes about 3 to 6 months of continuous therapy of Pentosan Polysulphate Sodium to see some benefit or improvement. However, the initiation of effect differs as Pentosan Polysulphate Sodium is recommended for long-term use to get effective clinical benefit. To check the effectiveness of Pentosan Polysulphate Sodium, patients are reviewed after 3 months of treatment. This is also done to analyse whether the medication can be continued longer if the patients have not had any side effects.
Do not take Pentosan Polysulphate Sodium without first consulting your doctor. If you are taking blood thinners such as warfarin, aspirin, heparin, etc., for any disease, inform your doctor as Pentosan Polysulphate Sodium can increase the risk of bleeding. Also, pregnant women, patients with kidney or liver problems should be cautious while using Pentosan Polysulphate Sodium.
Take Pentosan Polysulphate Sodium in the dose as advised by the doctor. Take it as whole with a glass of water at least 1 hour before meals or 2 hours after meals.
No, Pentosan Polysulphate Sodium should not be refrigerated. It should be stored at room temperature in a dry and dark place. Keep it away from reach of children.
